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Yuxuan Wang

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Open access Sep 2026

Hederagenin Attenuates Morphine Addiction via GABAA1‐Mediated Modulation of Ca2 +–CaMK–CREB Signaling in Ventral Tegmental Dopaminergic Neurons

ABSTRACT Morphine‐associated contextual reward learning promotes maladaptive drug–context associations during opioid exposure. Hederagenin (HE), a bioactive compound from traditional Chinese medicine, has neuroprotective potential, but its role in contextual reward learning remains unclear. Here, we investigated the ef...

Hong-Yan Jiang, Zi-Ting Zhou, Nan-Nan Xue et al. · 0 citations

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