Open access
Oct 2026
Polymer-photosensitizer conjugate exerting pH-responsive hydrophilic-to-hydrophobic conversion for cell-specific photochemical internalization of mRNA.
Cell-specific intracellular delivery of messenger RNA (mRNA) remains a challenge in the development of RNA therapeutics. Photochemical internalization (PCI) is a useful technology for the spatially controllable cytosolic delivery of such molecules in a light-selective manner, but cellular-level precision has yet to be...
Daiki Tokura, Yi-Ming Xia, Han-Qing Jiang et al.
· Biomaterials Advances · 0 citations