Design, Synthesis, and Fungicidal Activity Evaluation of 1,2,4-Triazole Fungicides Featuring gem-Difluoromethylthio Moiety.
The gem-difluoroalkylthio (-SCF2-) moiety has achieved great success in medicinal chemistry, but its application in agrochemicals remains underexplored because of synthetic challenges. Herein, we report a series of 1,2,4-triazole derivatives bearing the gem-difluoromethylthio group and evaluate their antifungal activit...