COMMON STRUCTURAL VARIANTS DRIVE TOP GWAS SIGNALS IN AUTISM AND RELATED NEURODEVELOPMENTAL DISORDERS
Background Genome-wide association studies (GWAS) have identified dozens of loci for autism and related neurodevelopmental disorders (NDDs), yet pinpointing causal variants remains challenging. Standard fine-mapping assumes the causal variant is a SNP present in reference panels, but common structural variants (SVs)—de...
Yundan Liao, Michael Gandal
· European Neuropsychopharmaco... · 0 citations