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Sponsored AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI

Author

Yun Zhang

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Oct 2026

hnRNPA2B1 sustains antitumor T cell immunity and enhances cancer immunotherapy through IDR-dependent stabilization of chromatin-regulatory transcripts.

T cell exhaustion within the tumor microenvironment poses a major barrier to effective cancer immunotherapy, yet the epigenetic mechanisms that preserve functional states of tumor-infiltrating T cells remain incompletely understood. Here, using an in vivo CRISPR screen, we identify heterogeneous nuclear ribonucleoprote...

Shi Liu, Wen-Yan Gao, Meng-Long Hu et al. · 0 citations
Open access Aug 2026

BACE2 Promotes Bladder Cancer Chemoresistance Through Proteolytic Activation of JAG1‐Notch Signaling

A novel BACE2‐JAG1‐Notch signaling axis that contributes to bladder cancer chemoresistance is defined and identified as a potential prognostic biomarker and a therapeutically actionable target to improve clinical outcomes in this disease.

Zekun Li, Sanxiang Li, Zhenyu Liu et al. · 0 citations

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