Author

Yun Yang

2 papers indexed here

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Sep 2026

Photocatalytic Four-Component Sulfonylation/ Ipso -Spirocyclization of N -Arylpropiolamides with Thianthrenium Salts, DABSO and H2O: Access to 3-Sulfonyl-Azaspiro[4.5]trienones

A visible-light-induced sodium fluorescein-catalyzed four-component cascade reaction of N-arylpropiolamides, aryl thianthrenium salts, DABSO, and H2O has been developed, providing efficient access to diverse 3-sulfonyl-azaspiro[4.5]trienones in moderate to good yields. The reaction accommodates a broad range of aryl...

Zi-Tong Zhang, Yun Yang, Jian Li et al. · Journal of Organic Chemistry · 0 citations

Sep 2026

A novel chimeric antimicrobial peptide B5PL dual-targets bacterial cell membrane and neutrophils to combat multidrug-resistant bacterial infections.

A novel chimeric antimicrobial peptide B5PL is designed by fusing a truncated bovine β-defensin 5 (B5) domain with a PL-5 derivative peptide (PL) to exert direct-indirect antibacterial activities and remodel immune homeostasis against MDR bacterial infections.

Ren-Ling Wang, Yun Yang, Yu-Ping Chen et al. · Bioorganic chemistry (Print) · 0 citations