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Author

Yun Xu

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2 papers indexed here

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Aug 2026

Nitroxide Polymer Encapsulating Triptolide for Safe and Effective Small Cell Lung Cancer Therapy by Targeting Energy Metabolism and Pyroptosis.

Small cell lung cancer (SCLC) is highly aggressive neuroendocrine tumor with a paucity of effective therapeutic option. Triptolide (TP), a natural diterpenoid triepoxide, exhibits potent antitumor activities, yet its efficacy and underlying mechanisms in SCLC remain largely undefined. Here, we demonstrate that TP effec...

Kuntan Wu, Yixuanchen Yu, Jiuzhi Xu et al. · 0 citations
Open access Sep 2026

Matrine Suppresses Lung Cancer Progression via Dual Inhibition of CHEK1‐Mediated DNA Damage Repair and PI3K/AKT Survival Signaling

Lung cancer remains a leading cause of cancer‐related mortality worldwide, necessitating the development of novel therapeutic strategies. Matrine, a natural alkaloid derived from Sophora flavescens, has demonstrated broad antitumor properties, yet its underlying mechanisms, particularly concerning DNA damage response,...

Jiang-Hao Yu, Si-Yang Chen, Ting-Ting Hou et al. · 0 citations

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