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Yun-Sang Tang

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Open access Sep 2026

Differential prolonged multiomic responses to mRNA and inactivated virus COVID-19 vaccines

Despite the significant impact of SARS-CoV-2 vaccines in curtailing the spread and severity of COVID-19, comprehensive omics-level understanding of longitudinal host responses remains elusive. We recruited 553 Hong Kong participants receiving two doses of CoronaVac (inactivated virus) or BNT162b2 (mRNA-based). Longit...

H. Tun, Shi-Lin Zhao, Chun-Ke Chen et al. · 0 citations
Open access Jul 2026

Somatic Evolution of a Germline Antibody Expands its Breadth to Neutralize Early SARS‐CoV‐2 Omicron Variants

The structural basis by which specific mutations enhance cross‐variant recognition of SARS‐CoV‐2 is defined, highlighting the underappreciated breadth encoded within the naïve B‐cell repertoire and providing a conceptual framework for engineering and eliciting antibody responses resilient to future antigenic drift.

Huibin Lv, Ziqi Feng, Q. Teo et al. · 0 citations

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