Open access
Aug 2026
Proximity-induced protein deglycosylation by endogenous O-GlcNAcase
Hai-Xing Xu, Bo-Wen Ma, Yun-Peng Huang et al.
· bioRxiv · 1 citation
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Sep 2026
Targeted O-GlcNAcylation enables functional rewiring of c-Myc.
An O-GlcNAcylation-targeting Chimera (OGTAC) is developed that recruits O-GlcNAc transferase (OGT) to the oncogenic transcription factor c-Myc, enabling targeted O-GlcNAcylation in living cells without globally perturbing cellular O-GlcNAcylation.
Tong-Yang Xu, Zhi-Hao Guo, K. S. Khan et al.
· Cell Chemical Biology · 2 citations