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Yun-Peng Hong

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#machine learning Preprint Oct 2026

ColdDDI: Evaluating Knowledge Utilization in Cold-Start Drug-Drug Interaction Prediction

Cold-start drug-drug interaction (DDI) prediction tests whether models can identify clinically significant interactions for drugs without training-time interaction history. Existing benchmarks mostly report aggregate edge-prediction scores, leaving a key evaluation question unanswered: when models receive molecular, te...

Ji-Heng Liang, Chen Zhao, Di Wu et al. · 0 citations

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