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Author

Yun-Dong Wu

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Oct 2026

SAEKP: A Site Attention Enzyme Kinetics Prediction Method to Facilitate Enzyme Engineering

While the determination of enzyme kinetic parameters traditionally relies on prolonged and costly experimental methods, machine learning models have recently demonstrated promise as predictive tools. These models still have limitations, such as limited training data and insufficient sensitivity to mutations at import...

Jia-He Qiu, Zong-Ying Lin, Ke-Wei Chen et al. · 0 citations
Aug 2026

TCRspec: A Recognition Interface-Informed Multimodal Method for TCR-pMHC Specificity Prediction.

TCRspec, an interpretable multimodal framework combining sequence embeddings, gene-usage features, and complex-level structural representations, providing a structure-informed framework for TCR specificity prediction, is developed.

Jia Zou, Zong-Ying Lin, Yi-Min Wang et al. · 0 citations

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