Open access
Aug 2026
Biallelic titin truncation disrupts sarcomere assembly and function in patient-derived iPSC-cardiomyocytes.
Using induced pluripotent stem cell-derived cardiomyocytes from a biallelic TTNtv patient with dilated cardiomyopathy, sarcomere structure/function is investigated and inefficient sarcomere assembly and interaction promotes cardiomyopathy in biallelic TTNtv.
Magnhild Sekse Erdal, Jing Qi, P. Erusappan et al.
· Journal of Molecular and Cel... · 0 citations