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Yukihiro Nakanishi

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Open access Aug 2026

Receptor-binding domain 2 of Clostridioides difficile binary toxin as a promising vaccine component against C. difficile infection

Symptoms of Clostridioides difficile infection (CDI) are primarily caused by two major protein toxins, toxin A (TcdA) and toxin B (TcdB). In addition, approximately 5-30% of C. difficile strains produce a third toxin, C. difficile binary toxin (CDT), which is has been associated with enhanced virulence and severe disea...

Shaohui Wang, Joshua Heuler, Yukihiro Nakanishi et al. · 0 citations

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