Discovery of the mechanism of Huangqi Guizhi Wuwu Decoction in the treatment of Diabetic Peripheral Neuropathy with Qi Deficiency and Blood Stasis based on the dynamic metabolic trajectory analysis.
ETHNOPHARMACOLOGICAL RELEVANCE Huangqi Guizhi Wuwu Decoction (HGWD), a classic Traditional Chinese Medicine formula, has shown clinical efficacy in the treatment of diabetic peripheral neuropathy (DPN) with Qi deficiency and blood stasis syndrome. However, its pharmacodynamic material basis and underlying therapeutic m...