TRDMT1-dependent m5C modification of TLR4 mediates the protective effects of Shaoyao decoction in TNBS-induced Crohn's disease.
BACKGROUND AND AIM Crohn's disease (CD) is a chronic inflammatory disease of the digestive system with increasing morbidity worldwide. Shaoyao Decoction (SYD), a traditional Chinese medicine formula, has shown therapeutic potential in the treatment of CD. However, the underlying mechanisms remain unclear. This study ai...