A two-step processing method is recommended to inactivate human sporadic M1 and V2 prions
Abstract Most human-acquired prion diseases result from infection with M1 or V2 prions from sporadic Creutzfeldt–Jakob disease. To prevent transmission via surgical instruments, sterilization methods targeting these prions are essential. In this study, stainless steel wires coated with M1 or V2 prions were used to eval...