Open access
Aug 2026
AAVR disruption as a producer-cell engineering strategy for enhanced supernatant-based recovery of selected AAV serotypes
In supernatant AAV vector recovery assays, AAVR knockout increased supernatant vector genome recovery for selected serotypes in a representative clone, although this effect varied among independently isolated clones.
Kenji Sakamoto, Kouhei Yoshida, Yuji Tsunekawa et al.
· Molecular therapy. Advances · 0 citations