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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

Yue Zhang

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Open access Sep 2026

Structural basis for broad orthopoxvirus neutralization by two antibodies targeting distinct L1R epitopes.

The 2022 mpox outbreak highlights the persistent threat posed by the mpox virus (MPXV) and related orthopoxviruses (OPXVs). Yet, approved antibody-based therapeutics for OPXVs are lacking. Here, we present two broadly neutralizing monoclonal antibodies (mAbs), G4 and B9, that target the MPXV M1R protein, homologous to...

Li Chen, Guan-Ying Zhang, Hao-Tian Lin et al. · 0 citations
Open access Sep 2026

Targeting BIRC6 rejuvenates hematopoietic stem cell aging and immunosenescence

It is revealed that regulatory T cells within the bone marrow microenvironment actively safeguard the survival of aged HSCs via a previously uncharacterized signaling pathway, and targeted BIRC6 inhibition in HSCs using antibody-conjugated lipid nanoparticle-encapsulated antisense oligonucleotides (LNP-ASOs) significan...

Wei-Nian Liao, Fang-Ze Shao, Shao-Yan Wang et al. · 0 citations
Review Open access Aug 2026

Stem-like CD4 T cells in tumors: an emerging framework for antitumor immunity

stem-like CD4 biology is presented as an emerging framework and established observations from working models are distinguished and established observations from working models are distinguished.

Jia-Xiang Xu, Yun-Chao Yang, Jun Zhang et al. · 0 citations

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