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Author

Yue-Yue Sun

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Open access 2026

A Novel Predictive Model for Perioperative Complications Following Valve Replacement in Severe Valvular Heart Disease

: Background: Valve replacement for severe valvular heart disease carries a risk of perioperative major adverse cardiovascular and cerebrovascular events (MACCE), which routine clinical indicators may help predict. Objective: To develop a machine learning model for predicting perioperative MACCE after valve replacement...

Guo-Feng Wang, Gao-Lei Wang, Hai-Lin Fu et al. · 0 citations
Sep 2026

Dual-drug conjugated ionizable lipids for nucleic acid delivery and multidimensional targeted therapy of brain tumors.

Lipid nanoparticles (LNPs) are the leading non-viral platform for nucleic acid delivery, and the structural design of ionizable lipids critically determines their delivery efficiency and therapeutic potential. Here, a dual-functional ionizable lipid was developed by integrating a vinpocetine-derived neurovascular regul...

Yue-Yue Sun, Dan-Dan Huang, Yue Qing et al. · 0 citations

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