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Author

Yue-Yue Huang

2 papers indexed here

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Open access Oct 2026

KLF4 Protects Against Sepsis-Induced Coagulopathy via Inhibition of the AKT/mTOR/STAT3 Signaling Pathway

Purpose Coagulation dysfunction is an independent predictor of morbidity and mortality in patients with severe sepsis, yet current therapeutic options remain inadequate. This study systematically evaluated the therapeutic potential of Krüppel-like factor 4 (KLF4) in sepsis-induced coagulopathy and explored the underlyi...

Rong-Rong Zhang, Yun-Jung Hong, Darong Hai et al. · 0 citations
Open access Sep 2026

Hypoxia-programmed apoptotic-mimetic M2 macrophage-derived small extracellular vesicles for hydrogel-mediated immunoregenerative bone repair

Effective regeneration of critical-sized bone defects requires the coordinated reconstruction of immune homeostasis, vascular networks, and osteogenic matrix formation. However, conventional bone-regenerative materials frequently provide structural support or single-pathway osteoinduction, while failing to actively orc...

Hao Pan, Jie-Feng Huang, Hao-Ze Zhu et al. · 0 citations

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