Yue Wang

Protein Lysine Lactylation in DNA Damage Response: Regulatory Mechanisms and Emerging Functions

Genomic DNA is constantly exposed to endogenous and exogenous stresses that can cause different types of DNA damage. DNA double-strand breaks (DSBs) are among the most damaging forms of DNA lesions, as persistent breaks can compromise genome stability. In response to such damage, cells activate DNA damage response (DDR...