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Author

Yue-Tong Yang

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Sep 2026

Mismatch-Engineered CRISPR Transistors for Ultra-Low-Frequency Single-Nucleotide Variant Detection

Accurate detection of low-frequency single-nucleotide variants (SNVs) in a high wild-type (WT) background remains challenging. Here, we report a mismatch-engineered CRISPR transistor (MECT) for rapid, amplification-free detection of mutant RNA. MECT integrates a Cas13a–crRNA recognition interface with a graphene fiel...

Chang Chen, Hongwenjie Ma, Han-Ting Xia et al. · 0 citations
Open access 2026

Blockchain Traceability Architecture Choice in Cross-Border Pharmaceutical Supply Chains: Robust Optimization and Break-Even Conditions

Cross-border pharmaceutical supply chains must choose a traceability architecture while coordinating procurement, production, bonded-warehouse inventory, customs execution, and fulfilment under uncertain demand. Existing blockchain assessments often compare predetermined scenarios without showing which operational mech...

Yue-Tong Yang, H. Hishamuddin, Abdul Hadi Azman · 0 citations

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