Author

Yue Liu

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Open access Sep 2026

Knowledge graph and machine learning-guided virtual screening prioritizes putative blockers of the PSMD11/Rpn6-EBOV glycoprotein interface

Host-directed antiviral discovery requires a traceable route from host-factor identification to testable molecular hypotheses. This study developed such a workflow around a host factor associated with Ebola virus glycoprotein (EBOV GP). GFP-GP pulldown coupled with co-immunoprecipitation/mass spectrometry wa...

Yan-Shuang Wang, Yuan-Jian Li, Lin Zhu et al. · Frontiers in Pharmacology · 0 citations

Open access Jul 2026

Integrative MeRIP-Seq and RNA-Seq Analyses Reveal Innate Immune and Infection-Related Transcriptomic Changes upon METTL3 Knockout

This study discovered that the METTL3 association with differentially expressed genes, suggested that METTL3 and the genes it regulates might serve as targets for defense against infection.

Qian Tang, Yong Hu, Lin Zhu et al. · Genes · 0 citations