The Biphasic Role of Reactive Oxygen Species in Ovarian Cancer Progression and Therapeutics: Crosstalk Among Metabolism, Ferroptosis, and the Tumor Immune Microenvironment.
Ovarian cancer (OC) is one of the most lethal malignancies of the female reproductive system, and its frequent recurrence and treatment resistance are major obstacles to improving patient outcomes. Studies indicate that the progression and treatment resistance of OC are driven by substantial metabolic and mitochondrial...