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Author

Yuan-Liang Sun

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Sep 2026

Spirometric Impairment and Incident Cardiovascular Disease: Beyond Airflow Limitation.

BACKGROUND Impaired spirometry is associated with cardiovascular disease (CVD), but it is unclear whether this risk is driven by airflow limitation or other spirometric dimensions. We compared spirometric phenotypes and lung-function measures in relation to incident CVD. METHODS We included 3,660 Sleep Heart Health S...

Yuan-Liang Sun, Jing Li, Zu-Hong Liu et al. · 0 citations
Aug 2026

MicroRNA-223-3p/NLRP3 axis attenuates LPS-induced sepsis-like myocardial dysfunction by suppressing cardiomyocyte pyroptosis

It is demonstrated that miR-223-3p attenuates LPS-Induced SLMD by inhibiting the NLRP3 inflammasome and cardiomyocyte pyroptosis and upon treatment with NLRP3 siRNA or a GSDMD-targeting pyroptosis inhibitor disulfiram, miR-223-3p failed to exert additional protective effects against SLMD.

Bi-Xue Zhang, Xin Li, Qianqian Xu et al. · 0 citations

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