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Yuan-Zhong Tu

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Open access Aug 2026

A Multi-Model Strategy for Optimizing Hepatitis B Virus preS1 Epitope Recognition by the Antibody HzKR127

Functional cure of chronic hepatitis B virus (HBV) infection remains a significant challenge, making viral-entry-blocking antibodies a promising antiviral strategy. Here, we developed a structure-guided computational workflow for affinity-enhancing candidate mutations at the interface between the humanized neutralizing...

Wen-Qing Chen, Yuan-Zhong Tu, Kai Wang et al. · 0 citations

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