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Yuan-Ting Zheng

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Open access Sep 2026

Adaptive introgression in Tibetans spans focal and distributed architectures

The findings reveal that adaptive introgression can contribute to complex human adaptation through functionally convergent combinations of archaic variants, rather than only through shared large-effect haplotypes.

Shen-Ao Liang, Qiong Zhu, Xin-Yun Gao et al. · 0 citations
Open access Aug 2026

Benchmarking RNA-seq with the Quartet and MAQC reference materials to establish best practices for accurate alternative splicing analysis

Previous limited characterization of short-read RNA-seq (srRNA-seq) accuracy in alternative splicing (AS) analysis due to methodological diversity and lack of reference standards, has left unclear how to achieve optimal performance—an issue increasingly critical with the rise of long-read sequencing. To address this, w...

Duo Wang, Jia-Xin Zhao, Qingwang Chen et al. · 0 citations
Preprint Aug 2026

TransNRank: Towards Accurate Neoantigen Ranking with Transformer

Personalized neoantigen prediction is challenging due to the scarcity of positive samples, the noise of the experimental data, the severe class imbalance trait and the complex of immunogenicity features. Prior arts, such as linear regression and XGBoost fail to model long-range dependencies and contextual relationships...

Zhiyin An, Yue-Nan Hou, Shumeng Duan et al. · 0 citations

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