Identification of candidate selenium-associated transcriptomic biomarkers in chronic obstructive pulmonary disease: an integrated bioinformatics and expression validation study
Introduction Chronic obstructive pulmonary disease (COPD) is marked by long-lasting airflow obstruction accompanied by persistent inflammation and disturbed redox balance. Although oxidative stress is well established in COPD, it remains unclear whether PBMC transcriptional patterns that co-vary with a curated selenium...