Epitope-Imprinted Polymer Nanoparticles Enable Selective Recognition of Filamentous Vimentin for Tumor Imaging In Vivo.
Vimentin is a cytoskeletal protein upregulated during epithelial-mesenchymal transition that can also be aberrantly displayed on the surface of multiple tumor cell types, making it a promising target for tumor imaging. Here, we develop epitope-imprinted polymer nanoparticles (nanoMIPs) for vimentin recognition through...