Open access
Aug 2026
Multi-layered molecular regulation of complex traits in an advanced intercross line
Most complex-trait-associated variants reside in non-coding regions, yet functional annotation relies heavily on static local expression quantitative trait loci (cis-eQTL), leaving distal and context-dependent regulatory effects unresolved. Here, we leverage an 18-generation chicken advanced intercross line, which subs...
Xiao-Ning Zhu, Cheng-Hao Zhai, Chong Li et al.
· bioRxiv · 0 citations