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Open access Aug 2026

Dynamic junction remodeling and transient vascular disruption during cancer cell extravasation across the blood-brain barrier

Brain metastasis is the major cause of cancer-related mortality and remains a critical challenge in clinical oncology. Extravasation of circulating cancer cells across blood-brain barrier (BBB) is the first crucial and rate-limiting step for brain metastasis growth. However, the dynamic changes of brain endothelial cel...

Yu Zhang, Shun-Ze Deng, Yong-gang Ren et al. · 0 citations

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