Yu-Ying Wang

Azoreductase-Responsive Self-Assembled 10-Hydroxycamptothecin Nanofibers for Tumor-Specific Imaging and Therapy

Hypoxia is a defining feature of the tumor microenvironment (TME). The overexpression of azoreductase (AzoR) in hypoxic conditions enables it to serve as a trigger for drug release in tumor therapy. Developing a theranostic agent that is selectively activated in TME is vital for enhancing anti-tumor efficacy while mi...