Modular Whole-Cell Transaminase Cascades for Bioamination of Biomass-Derived Aldehydes through Amino-Donor Regeneration and Pyruvate Removal
The biocatalytic conversion of lignocellulose-derived aldehydes into value-added aromatic and heteroaromatic amines is often restricted by the reversibility of transamination, inefficient amine-donor utilization, pyruvate accumulation, and insufficient intracellular cofactor regeneration. In this study, three modular...