Beyond the brain-centric view: A systems physiology framework for exercise-induced neuroprotection in Alzheimer's disease.
Alzheimer's disease (AD) is regarded as a multifactorial disease that combines central pathological changes and peripheral organ dysfunction. Its core features include Aβ protein deposition, tau protein pathology, synaptic dysfunction, and neuroinflammation. Exercise has been proven to be one of the most effective non-...