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Yu-Xian Liu

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Review Open access Oct 2026

Cell–Cell Communication in Embryonic Kidney Development: Insights from Single-Cell and Spatial Transcriptomics

Embryonic kidney morphogenesis depends on the coordinated communication among ureteric epithelium, nephron progenitors, stroma, endothelium and differentiating nephrons. Classical studies established central roles for glial cell line-derived neurotrophic factor (GDNF) signaling through the RET proto-oncogene receptor t...

Le-Ping Wang, Xue-Jia Zheng, Feng Zhu et al. · 0 citations
Review Open access Sep 2026

Deep Learning-Assisted Prioritization of Candidate Drug Targets in Tumors Using Spatial Multi-Omics

Simple Summary Cancer treatment is often complicated by the fact that tumor tissues are not uniform. Different cells occupy distinct locations, communicate with nearby cells, and respond differently to treatment. Spatial multi-omics provides a way to examine these differences while preserving information about where bi...

Yu-Xian Liu, Xu Zhou, Jun-Yuan Zhang et al. · 0 citations
Open access Aug 2026

Integrated Transcriptomic Analyses Identify Four Prognosis-Associated Genes in Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC) is one of the malignant tumors with high incidence and mortality rates worldwide. Given the poor prognosis of patients with HCC, it is crucial to explore the molecular mechanisms underlying HCC development and to evaluate prognostic markers. Differential expression analysis followed by un...

Yu-Xian Liu, Xing-Jie Chen, Jun-Yuan Zhang et al. · 0 citations

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