Author

Yuwei Li

2 papers indexed here

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Open access Sep 2026

Wdr5 Modulates Synaptic Development and Memory Consolidation in the Hippocampus and Cerebral Cortex.

WD-repeat domain 5 (Wdr5), a core component of the SET1/MLL family of histone methyltransferases, is widely involved in the regulation of development, epigenetic control, transcription, and cell division. Wdr5 has been linked to neurodevelopmental disorders characterized by intellectual disability and developmental del...

Hui-Shan Wang, Wei Li, Peng-Cheng Ma et al. · Journal of Molecular Cell Bi... · 0 citations

Open access Jul 2026

The E3 Ubiquitin Ligase RLIM Safeguards Oligodendrocyte Development and Myelination by Targeting SLC7A11 for Polyubiquitination to Regulate Ferroptotic Resistance

ABSTRACT In the central nervous system, oligodendrocytes (OLs) generate myelin sheaths to support rapid nerve impulse conduction. OL lineage cells, especially oligodendrocyte precursor cells (OPCs), feature high metabolic activity and are exposed to severe oxidative stress, but the protective mechanisms remain poorly u...

Yuwei Li, Haijun Zhang, Jieya Zhou et al. · Advancement of science · 0 citations