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Yu-Rong Dong

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Open access Sep 2026

Glut1 and MCT4 cooperatively promote ccRCC cell proliferation and are associated with glycolytic reprogramming and immune-related alterations.

Clear cell renal cell carcinoma (ccRCC) is characterized by glycolytic reprogramming and a lactate-rich tumor microenvironment. We integrated multi-omics, single-cell, tissue microarray, and in vitro analyses to investigate the roles of Glut1 and MCT4 in ccRCC. Both transporters were upregulated at the mRNA and protein...

Kun Cui, Yu-Zhi Zhu, Yue-Li Ni et al. · 0 citations

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