Theta phase-targeted prefrontal stimulation modulates amygdala gamma oscillations and alleviates depressive-like behavior in CUMS rats.
AIMS Depression is a prevalent and treatment-resistant disorder often linked to dysfunctional communication between the medial prefrontal cortex (mPFC) and basolateral amygdala (BLA). A key mechanism involves impaired inhibitory control from the mPFC, leading to aberrant theta and gamma oscillations in the BLA. Althoug...