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Yu-Qing Hu

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Open access Sep 2026

Right ventricular pressure overload disturbs T-tubule maturation via MEF2D’s transcriptional regulation of BIN1

Right ventricular pressure overload (RVPO) is a critical pathophysiological feature of numerous pediatric cardiovascular diseases. Transverse tubules (T-tubules) form the foundation for efficient excitation-contraction coupling in mature cardiomyocytes. We hypothesized that RVPO impairs T-tubule maturation through the...

Yu-Qing Hu, Yi-Ting Xue, Xu-Dong Chen et al. · 0 citations

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