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Author

Yulan Jin

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Open access Sep 2026

α-Herpesviruses exploit host ssDNA gap prevention pathways for GC-rich genome replication and reactivation.

Many α-herpesviruses, such as herpes simplex virus type 1 (HSV-1) and pseudorabies virus, possess GC-rich genomes prone to forming G-quadruplex (G4) structures. However, the impact of these G4 structures on viral genome maintenance is unknown. Here, we demonstrate that G4s impede lagging strand DNA synthesis in the vir...

Juan Zhang, Meng-Jiao Lan, Hui-Guo Fu et al. · 0 citations
Open access Aug 2026

Development and application of a novel TaqMan qPCR assay targeting the gN gene for genotyping pseudorabies virus

Young pigs are more susceptible to PRV and the infection in piglets is nearly 100% fatal, whereas adult pigs exhibit reproductive disorders such as abortion, stillbirths, and reduced fertility, ultimately decreasing farm productivity.

Yu-Lan Jin, Xuan Ji, Weiren Dong et al. · 0 citations

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