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Yu-Jing Hu

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Sep 2026

The Catalytic Oxidative Cyclization Synthesis of Isochromanoindolenines by Multicopper Oxidase in a Microflow System

Herein, we disclose a microflow system-mediated oxidative cyclization process catalyzed by multicopper oxidase, employing 2,3-dihydroxybenzoic acid and a range of substituted tetrahydrocarbazoles to afford structurally complex isochromanoindolenines. The reaction proceeds under mild conditions without the need for ex...

Shu-Zhan Wang, Qian-Xi Zhou, Xue-Ming Wang et al. · 0 citations
Jul 2026

Biocatalytic Dynamic Kinetic Resolutions Enable Enantiodivergent Access to Axially Chiral Biaryl Dimethanols via Transient Seven-Membered Lactols

Axially chiral biaryl dimethanols are ubiquitous and multifunctional intermediates for the synthesis of valuable atropisomeric molecules in advanced materials, drugs, natural products, and organocatalysts. Despite their broad synthetic utility, direct enantiodivergent catalytic access to this specific class of compou...

Jie Chen, Zhuoting Peng, Xiaolong Gao et al. · 0 citations

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