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Author

Yu-Jie Ma

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Open access Sep 2026

Sestrin2 mitigates obesity-associated HFpEF via adaptive IRE1α-XBP1 signaling and redox regulation.

It is demonstrated that Sestrin2 has cardioprotective effects on obesity-associated HFpEF and is associated with the activation of adaptive IRE1α-XBP1 signaling involving Sigmar1, together with improved metabolic and redox homeostasis.

Ke-Xin Zhang, Cheng-Xia Kan, Jing-Wen Zhang et al. · 0 citations
Jul 2026

Rising Global Burden and Sex Disparities in Nonmelanoma Skin Cancer: 1990-2021 Trends With Projections to 2036.

The global burden of NMSC is rising, and men consistently experience higher incidence, mortality, and DALY rates than women, and the expanding sex gap highlights the urgent need for targeted and sex-specific prevention, early detection, and public health interventions.

Wenqiang Zhang, Ke-Xin Zhang, Cheng-Xia Kan et al. · 0 citations

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