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Author

Yu-Jiao Chen

2 papers indexed here

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Open access Aug 2026

Mechanistic basis of LolDF-mediated lipoprotein transport in Acinetobacter

Lipoprotein trafficking is essential for Gram-negative bacteria to maintain the outer membrane, a permeability barrier critical for survival and antibiotic resistance. While most bacteria employ the canonical LolCDE transporter, Acinetobacter utilizes a noncanonical LolDF system whose mechanism has remained unclear. He...

Jie Pang, Ya-Wen Chen, Wen-Long Qiao et al. · 0 citations
Open access Jul 2026

Mechanistic insights into TAM-mediated OMP assembly in Gram-negative bacteria.

The β-barrel assembly machinery (BAM) is essential for outer membrane protein (OMP) biogenesis in Gram-negative bacteria and represents a validated target for antibiotic development. Its evolutionary relative, the translocation and assembly module (TAM), is thought to assemble OMPs but through a mechanism that remains...

Qinghua Luo, Xintan Dong, Zhaxi Zerang et al. · 0 citations

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