Author

Yu Hou

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Review Aug 2026

One ligand, multiple fates: the multi-receptor signaling network of FSTL1 and receptor-selective intervention strategies.

A receptor-centered framework for understanding the functional complexity of FSTL1 is proposed and receptor-selective intervention strategies for cardiovascular, fibrotic, inflammatory, and malignant diseases are discussed.

Yu Hou, C. Fang, Wen-Qi Yang et al. · Biochemical Pharmacology · 0 citations

Review Open access Sep 2026

GPR75: A Dual-Ligand Receptor for 20-HETE and CCL5 with Emerging Roles in Central and Peripheral Regulation of Metabolic Diseases.

G protein-coupled receptor 75 (GPR75) has recently attracted considerable attention as a novel regulator of metabolic, immune, and vascular processes. Current evidence suggests that two structurally distinct molecules have been proposed as candidate endogenous ligands for GPR75: 20-hydroxyeicosatetraenoic acid (20-HETE...

Yu Hou, Shu-Jing Liu, Liang-Ming Li · Pharmacological Research · 0 citations