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Author

Yu-He Xiao

2 papers indexed here

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Sep 2026

HDACiAP: A Curated Database and Analytical Platform for Histone Deacetylase Inhibitors.

Histone deacetylases (HDACs) are pivotal epigenetic regulators that are aberrantly expressed in various cancers, making them prominent targets for anticancer drug development. Herein, we present HDACiAP (https://hdac.kangsgo.cn), a meticulously curated, comprehensive database and analytical platform dedicated to HDAC i...

Yu-He Xiao, Jia-Ping Ou, Jia-Tong Chen et al. · 0 citations
Oct 2026

Targeting ZDHHC15-mediated S-acylation of CD155 reactivates anti-tumor immunity.

The immune checkpoint CD155 is frequently upregulated across multiple malignancies and drives tumor progression and immune evasion, yet the posttranslational mechanisms regulating its stability and activity remain unclear. Here, we identify S-acylation as a key regulator of CD155 stability and immunosuppressive functio...

Xuan-Pu Zhang, Jie Zou, Jian Lin et al. · 0 citations

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