The Multifaceted Roles of Macrophages in Rheumatoid Arthritis: From Cytokine Networks to the Discovery of Novel Subsets
Macrophages play a central and multifaceted role in the pathogenesis of rheumatoid arthritis (RA). This review synthesizes current understanding, emphasizing how M1/M2 polarization imbalance drives RA progression. Specifically, M1 promotes synovial inflammation, joint destruction, and pannus formation via pro-inflammat...