We developed EASI-PASS, a reliable, high-throughput method for estimating the molecular identity of functionally characterized cells by merging live imaging with subsequent fixed-tissue imaging using conventional microscopes. Our method matches the shapes and locations of thousands of densely imaged cells between large...
Jonnathan Singh Alvarado, Crystian I. Massengill, Josh Stern et al.· bioRxiv· 0 citations
A central challenge in neuroscience research is to elucidate how distinct neuronal types coordinate to produce complex behaviors, which requires linking the molecular identity of neuronal types with their connectivity and activity in behaving animals. Here, we present a protocol for integrating spatial gene-expression...
Risa Yamazaki, Mark Eddison, Anja Payne et al.· STAR Protocols· 0 citations
A central challenge in systems neuroscience research is to elucidate how distinct neuronal cell types coordinate to produce complex behaviors: an endeavor that requires linking their molecular identity, connectivity and activity patterns in behaving animals. Recent advances in single-cell RNA sequencing and spatial tra...
Risa Yamazaki, Mark Eddison, Anja Payne et al.· bioRxiv· 1 citation
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