Review
Jul 2026
Microglial immunometabolic reprogramming in Alzheimer's disease: From mitochondrial dysfunction and redox imbalance to NLRP3 inflammasome-driven neuroinflammation
A stage-dependent mitochondrial dysfunction–redox imbalance–NLRP3 inflammasome axis provides a testable stage-dependent framework for interpreting chronic, self-amplifying neuroinflammation in AD and may inform biomarker-guided, combinatorial therapeutic strategies.
Si-Yu Li, Jun-Tao Jin, Ying-Ying Liu et al.
· Journal of Alzheimer's Disea... · 1 citation