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Open access Sep 2026

Vagus Nerve Stimulation Exerts Disease-Modifying Effects in Epileptic Rats by Enhancing Hippocampal Adenosine Signalling.

OBJECTIVES Vagus nerve stimulation (VNS) is an established neuromodulatory therapy for refractory epilepsy, but its disease-modifying mechanisms remain unclear. Adenosine is an endogenous anticonvulsant and a key regulator of epileptogenesis, and adenosine kinase (ADK) controls extracellular adenosine availability. Thi...

Zhong-Hua Xiong, Jing Zhang, Ran Gao et al. · 0 citations
Open access Oct 2026

Ictal Epileptogenic Network Differences in Posterior Cingulate Epilepsy Subtypes Based on SEEG

ABSTRACT Aims To compare differences in ictal propagation between epileptogenic networks between posterior cingulate cortex (PCC) epilepsy and retrosplenial cortex (RSC) epilepsy and to elucidate their network‐level pathophysiological characteristics. Methods A total of 18 patients with confirmed PCC or RSC‐related epi...

Zhao-Fen Yan, Yu-Jiao Yang, Jing Wang et al. · 0 citations
Open access Aug 2026

Implantable vagus nerve stimulation for the treatment of disorders of consciousness with epilepsy: a retrospective propensity score-matched clinical study

Implantable VNS was associated with higher 1-year clinically meaningful improvement and greater longitudinal CRS-R gains than conservative management in DoC patients with epilepsy and to explore factors related to response.

J. Zuo, K. Ma, Zi-Zhang Cheng et al. · 0 citations

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