Author

Yu-Feng Shen

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Review Open access Jul 2026

Rationale and Methods for the Prospective Genetic Risk Evaluation and Assessment (PROGRESS) in Autism Center at Columbia University.

By linking early genetic probability with brain-behavioral trajectories, PROGRESS advances understanding of autism-related differences before clinical diagnosis and provides an empirically grounded foundation for ethical genomic newborn screening and optimized early developmental monitoring and intervention.

Nicolò Pini, L. Shuffrey, Kally C. O'Reilly Sparks et al. · Pediatric Research · 0 citations

Jul 2026

Understanding language model scaling for protein fitness prediction

It is shown that model size, training dataset and stochastic elements can bias the predicted p(sequence) away from real fitness, which clarifies the scaling behavior of protein models on fitness prediction and provides practical guidelines for their application and future development.

Chao Hou, Di Liu, Aziz Zafar et al. · Nature Computational Science · 2 citations